Sodium L- Ascorbate is a buffered form of Vitamin C and as such, it is located in nature.
Food which contains vitamin C:
- All fruits of the genus lemons, tomatoes, parsley, iris, horseradish, green peppers, radishes, green leafy vegetables, raw, nettles, spinach;
- Red, orange and yellow fruits: pomegranate, red pepper
- Melons, strawberries, black and red currants, cherries, green walnuts whose core is still soft, blackberry, grape leaves, cabbage, potatoes, kale, Brussels sprouts, beet greens, white pepper, pine needles (tea). Rosehip is 120 times as rich in vitamin C from orange.
Thanks to its genesis, vitamin C is directly related to chlorophyll. Green leaves and parts of wild red fruits are considered to be the richest in this vitamin.
Preservation and activation
The smallest amount of it is found in the underground organs of plants, but as the seeds start to germinate so does concentration of c vitamin grows.
It is preserved in an acidic environment (eg. In dried fruit not). Vitamin C is lost by boiling (oxidized), by heating, by grinding. It is also lost, when comes in touch with air and the contact with the alkali cooking utensils made of copper. It is the most sensitive of all water-soluble vitamins. Oxidation happens not only at high but also at room temperature, which destroys him. It is being destroyed on at a temperature of 60 ° C (dry heat), or in water vapor under pressure at 120 ° C. Neither at a low temperature is not kept well, but quick freezing of fruits and vegetables at least injury (e.g., potato cooled and stored at 3 – 5 ° after six months still has 90% of vitamin C). In the alkaline environment is rapidly lost due to oxidation under the influence of oxygen from the air. To keep your losses to a minimum it is recommended shorter cooking in less water. It is also destroyed by sulfur dioxide, sulfuric acid, the sodium bisulfate and others compounds of sulfurous acid that are used for preservation.
When is consumed together with a milk, vitamin c is being inactivated.
After three days of storage, spinach loses almost all this vitamin. Green beans and dandelion losses up to 80% of the stated amount, while dried fruits and vegetables lose it completely.
Mushrooms have no vitamin C.
Biochemistry and role
Vitamin C has a special role in the hydroxylation of proline into collagen. It is necessary everywhere in the metabolism. It has a half-life of 16 days (to develop scurvy takes 3 – 4 months).
- a) to maintain the intercellular material;
- b) A specific role in the synthesis of collagen, that is in the synthesis of the hydroxyproline or proline;
- c) In oxidation-reduction systems: glutathione, cytochrome C, pyridine or flavin nucleotides nucleoproteins;
- d) The oxidation of tyrosine; e) in the metabolism of adrenal steroids;
- f) In the metabolism of various drugs.
Point a) explains the importance of all functions of the organism. With point b) explains its important role in the function of connective tissue and wound healing.
From the point c) to f) function is not specific, because it can be replaced by other compounds which have similar redox characteristics.
Vitamin C is available in 4 stereo-isomeric forms (LL, DD, LD, DL). LL is the most active form – Sodium L-ascorbate.
- carnitine is synthesized from the amino acid lysine. For the synthesis of an essential vitamin C.
- Bark adrenal gland contains a large amount of vitamin C, and it is rapidly reduced when it is stimulated by adrenocorticotropic hormone.
The human body and vitamin C
A similar reduction is observed in experimental animals when they have been received the injections of diphtheria toxin. When it comes to the infection (fever), especially in the presence of bacterial toxins, humans also have a decrease in the amount of vitamin C in the adrenal cortex. This indicates that plays an important role in organism”s reaction to stress. The adrenal gland is usually required in order to convert cholesterol into hormones (corticosteroids). In the hydroxylation reactions of amino acid tyrosine, dopa is formed first, then dopamine, and norepinephrine. Adrenaline, a hormone important in stress, is formed in the end and it protects Vitamin C from oxidation.
Liver, brain, and gastrointestinal tract have a ten times higher concentration of vitamin C than other localizations. Very high concentrations were found in the pituitary gland, thyroid gland, adrenal gland, ovarian corpus luteum, the eye lens, leukocytes, and spleen.
In general, the tissue with the highest metabolic activity has the highest concentration of Vitamin C, except muscle. The concentration of vitamin C in the brain is high even in scurvy when the concentration of vitamin C in all tissues and liquids falls to zero. The amount of vitamin C in the ocular humor is 18 – 25 times the amount in the plasma;
- Increases the elimination of uric acid in the urine;
The biggest part of the endogenous urinary oxalate represents ascorbic acid. Sixty-five percent of vitamin C is excreted through the kidneys. High doses lead to a drop in pH of urine. Increased ability to create calcium oxalate stones in the kidney or urinary tract. It is important to note that the use of Na-ascorbate prevents possible complications by a urinary tract infection.
- reduces the amount of sugar in the cell, because it competes with the receptors for sugar transport to the cell membrane. Vitamin C can cause false positive results in glucose in the urine of diabetics. For each gram of Vitamin C, taken orally, a need for insulin in diabetes is reduced by two units;
- reduces platelet aggregation;
The coronary epidemic is considered to be a new version of the old scurvy. The level of vitamin C fall in the level of scurvy 6 – 12 hours after a heart attack or an attack of angina pectoris. The concentration of vitamin C in leukocytes also falls and remains low for several weeks after a heart attack, to be later gradually, reduced. Vitamin C reduces mortality in people with cardiovascular disease by 20 – 60%;-reduces capillary permeability;
- Vitamin C reduces the number and size of the gallstone (not prevent the formation);
- Increases the effectiveness of the immune system. It stimulates the production of interferon. Vitamin C accelerating production (increased blastogenesis) of lymphocytes. It Activates macrophages (via interferon). Increases the production of antibodies. Prostaglandins (lipids, hormones) participate in the regulation of heartbeat, blood flow, restore the damaged cells agents in the reactions of the immune system. This can be controlled by aspirin, and vitamin benefits of vitamin C over the aspirin are obvious.
Experimentally – it is able to completely stop the malignant transformation of cells. Vitamin C Sodium L-Ascorbate is selectively toxic for malignant melanoma, and its efficacy is greatly increased with a small amount of copper.
Patients suffering from cancer generally have a low concentration of Vitamin C in plasma and leukocytes (50%). Nitrates and nitrites (bacon, dry or canned meat, etc.), reacts with amino acids in the stomach and creates highly carcinogenic nitrosamines, which are one of the causes of stomach cancer.
Vitamin C destroys the nitrite and nitrate and protects us from stomach cancer.
For this effect, the daily requirement of vitamin C Sodium L-Ascorbate must be taken with every meal (due to the presence in the stomach). Vitamin C slows down the growth of the tumor. Increases the average length of survival of cancer patients, while improving the general condition. According to one reports previous chemotherapy or radiation therapy reverses the effects of vitamin C and reports the same to other therapy has no influence on the effects of vitamin C, the stimulus tissue regeneration;
Vitamin C, especially in high doses, increases the amount of estrogen (handled with care during pregnancy because of the potential pre-term labor).
Many books say that taking 4 – 12 g / d of vitamin C may cause urinary tract deposition of urate and cystine stones. People who are prone to gout, the formation of stones, or cystinuria must avoid large amounts of vitamin C. This statement is incorrect. The acidity in the urine is increased the ascorbic acid, not by vitamin C, because he may take the form of Sodium L-Ascorbate acid that does not increase the acidity of urine.
Vitamin C is, in fact, the ascorbate ion, negative charge and is bonded to the ascorbic acid in the proton (H +), and the sodium ascorbate in the sodium ion (Na +) and so on.
- Indicated toxic characteristics in tobacco, carbon monoxide, arsenic compounds, cyanide, mercury, lead, strychnine, heroin, alcohol, ozone, bacterial toxins and bacterial toxins. Detoxifying toxins diphtheria, tetanus, staph, and dysentery bacillus Products’ causes typhoid fever.
One smoked cigarette destroys 25 – 100 mg of vitamin C.
When there is a lack of vitamin C, the metabolic capability of the liver to detoxify drugs is decreased, especially in the elderly population. In this case, there is a risk of overdose and intoxication.
If vitamin C is put into a glass of water before drinking it quickly and effectively destroys chlorine, which damages red blood cells. Chlorine from water is particularly damaging to red blood cells of kidney patients in whom anemia under the influence of chlorine is formed much easier. Adding vitamin C to the water for dialysis neutralize the chlorine.
Vitamin C protects the body of the tannic acid (tea).
People cannot synthesize ascorbic acid, because they do not have the enzyme to convert L-ascorbic acid in gluconolactone. Neither guinea pigs nor man can synthesize ascorbic acid. Guinea pigs, as well as human, are having the ability from suffering of; scurvy, anaphylactic shock, toxic poisoning diphtheria, tuberculosis, neurotrophic leukemia which is in no way different from that of men. None of the laboratory animal that synthesizes vitamin C (rabbit, rat, rabbit, etc.) are not affected by a said disease.
If all of a sudden we stop the intake of vitamin C, after the previous high daily doses, there will be a conversion of the entire available ascorbic acid in the other substance.
This will result in an unusually low concentration of ascorbic acid and dehydroascorbic acid in the blood. This effect lasts for 1 – 2 weeks (“rebound effect”), during which the amount of enzyme is reduced to normal, and the ascorbic acid concentration is normalized. If it is desired, the daily dose should be gradually reduced.
- Power vitamin C rapidly increases during menstruation, especially during ovulation. Metering of ascorbic acid can thus serve as an indicator of cessation of ovulation, and can help in the determination of the most suitable moment of conception;
Pregnant women have a greater need for vitamin C, because vitamin C is required for the development of the embryo, and smooth is transferred through the placenta. Vitamin C concentration in the umbilical cord is four times greater than the concentration in the blood of the mother. Vitamin C is excreted through breast milk. At birth, the infant is well supplied with vitamin C, or from sixth to twelfth-month child develops scurvy if besides to milk do not take fruits and vegetables. These newborn infants with a reduced concentration of ascorbic acid are prone to lesions.
- Vitamin C – 70 mg / kg body weight. Reserves totaling 5,000 mg, and range from 1,500 mg – 5,000 mg. According to these calculations to the reserve of 5.000 mg held constant it is necessary to the input of 200 mg / d (under ideal conditions). 60 mg in the circulation (metabolism);
- Deadly dose does not exist;
A man can take orally vitamin C for ages, in a dose of 10 – 20 g / d;
Sodium L-Ascorbate is taking care also for urine alkalization.
- A good daily dose of vitamin C is the dose which provides a constant maximum saturation of our tissues because it is so in all living organisms in organisms which can synthesize;
- Sudden discontinuation of vitamin C can be dangerous because of the “rebound effect”, which lasts about two weeks;
- Unlimited is provided if it is stored in the form of fine crystals or crystalline powders Na L-ascorbate in brown or white crystal bottles. Capsules are stored in the same way;
Hypovitaminosis of vitamin C:
- Slight symptoms: swelling and bleeding from the gums, the porosity of the dentin hiperkeratotički the hair follicles;
- Hardly symptoms: extensive changes in the muscles, muscle pain, joint swelling, dilution bones and fragile bones, increased capillary permeability, striking tendency to bleeding and bruising gaining, extravasation of blood into the spaces between the fascia, anemia, loss of appetite, loosening and falling out teeth, poor wound healing, reduced resistance to infection.
- In the prevention of SIDS (sudden infant death syndrome) is recommended vitamin C (see, and it H);
- Often forms in which a deficiency of vitamin C exhibits are:
The immune system: the secondary infection, rheumatoid arthritis, collagen diseases.
Packing: 90 and 60 pieces of capsules, and powder of 150gr and 75gr.
The expert team of company LV-Pharm doo, Beograd